How diabetes affects platelet function and increases heart attack risk
Platelet Metabolism in Diabetes Mellitus
This study is looking at how type 1 diabetes affects blood platelets, which are important for stopping bleeding, to see if high blood sugar makes them more active and increases the risk of heart problems; we're hoping to find new ways to help keep your heart healthy if you have diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10884522 on NIH RePORTER |
What this research studies
This research investigates the relationship between type 1 diabetes mellitus (T1DM) and platelet activity, which is crucial for blood clotting. It aims to understand how high blood sugar levels lead to increased platelet activation and the formation of blood clots, which can result in heart attacks and strokes. By using advanced techniques to analyze platelet metabolism, the study seeks to identify new therapeutic strategies that could reduce cardiovascular risks for patients with diabetes. Patients may be involved in the research to help uncover these mechanisms and test potential treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes mellitus who are at risk for cardiovascular events.
Not a fit: Patients without diabetes or those with type 2 diabetes may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce the risk of heart attacks and strokes in patients with diabetes.
How similar studies have performed: Previous research has shown that understanding platelet function in diabetes can lead to significant advancements in cardiovascular treatment, indicating a promising avenue for this study.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Wang, Qingjun — University of Kentucky
- Study coordinator: Wang, Qingjun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.