How diabetes affects blood flow in the brain and dementia risk in older adults
Intracranial arterial compliance, cerebral blood flow, and dementia risk in older adults with type 2 diabetes
This study is looking at how type 2 diabetes might affect the brain and increase the risk of dementia, especially Alzheimer's, in older adults, and it aims to find early signs of memory problems so that people can get help sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10800678 on NIH RePORTER |
What this research studies
This research investigates the relationship between type 2 diabetes and the risk of developing dementia, particularly Alzheimer's disease, in older adults. It focuses on understanding how diabetes impacts cerebral blood flow and arterial compliance, which are crucial for brain health. By using advanced MRI techniques, the study aims to identify early signs of cognitive decline before significant brain damage occurs, allowing for timely interventions. The goal is to improve outcomes for individuals at risk of dementia due to diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults with type 2 diabetes who are at risk for cognitive decline.
Not a fit: Patients without type 2 diabetes or those who are not in the older adult age group may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and prevention strategies for dementia in older adults with diabetes.
How similar studies have performed: Previous studies have shown promising results in understanding the links between diabetes and cognitive decline, but this approach using advanced MRI techniques is relatively novel.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Bangen, Katherine — University of California, San Diego
- Study coordinator: Bangen, Katherine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.