How diabetes affects blood flow in the brain and dementia risk in older adults

Who could benefit from this research

What this research studies

This research investigates the relationship between type 2 diabetes and the risk of developing dementia, particularly Alzheimer's disease, in older adults. It focuses on understanding how diabetes impacts cerebral blood flow and arterial compliance, which are crucial for brain health. By using advanced MRI techniques, the study aims to identify early signs of cognitive decline before significant brain damage occurs, allowing for timely interventions. The goal is to improve outcomes for individuals at risk of dementia due to diabetes.

Why it matters

Where this research is happening

• University of California, San Diego
  La Jolla, United States Active

Researchers

• Principal investigator: Bangen, Katherine — University of California, San Diego
• Study coordinator: Bangen, Katherine

Related research

Other NIH-funded projects on the same topics.

• How diabetes affects blood flow and dementia risk in older adults

  This study is looking at how type 2 diabetes might affect the brain and increase the risk of dementia, especially Alzheimer's, in older adults, and it hopes to find early signs of memory problems so that people can get help before serious issues develop.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11040402

• Investigating the impact of dietary compounds on cognitive decline in older adults with diabetes

  This study is looking at how certain foods and substances in the blood, called Advanced Glycation End products (AGEs), might affect memory and thinking skills in older adults with type 2 diabetes, to see if reducing these levels could help prevent dementia.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-10889801

• How type 2 diabetes affects brain health and dementia risk

  This study is looking at how not managing type 2 diabetes and prediabetes can affect brain health and memory in young adults aged 18 to 45, and it wants to find out if better diabetes management can help keep your mind sharp.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10854563

• Subtyping Core for Research on the Causes of Type 2 Diabetes (SCORE-T2D)

  A new U01 grant from a university research team aims to understand why Type 2 diabetes differs so much between people and how to tailor prevention and treatment.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11617648

• Michigan Diabetes Project: A Peer-Led Self-Management Program for Adults with Type 2 Diabetes

  A peer-led self-management program for adults with type 2 diabetes is being tested to see if it improves blood sugar control and daily diabetes care.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11594416

• Alzheimer’s and dementia risk in people with prediabetes or type 2 diabetes

  This grant aims to understand why some older adults with prediabetes or type 2 diabetes develop memory problems or dementia.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11585476

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.