How diabetes affects blood flow and dementia risk in older adults
Intracranial arterial compliance, cerebral blood flow, and dementia risk in older adults with type 2 diabetes
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11040402
This study is looking at how type 2 diabetes might affect the brain and increase the risk of dementia, especially Alzheimer's, in older adults, and it hopes to find early signs of memory problems so that people can get help before serious issues develop.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11040402 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between type 2 diabetes and the risk of developing dementia, particularly Alzheimer's disease, in older adults. It focuses on understanding how diabetes impacts cerebral blood flow and arterial compliance, which are crucial for brain health. By using advanced MRI techniques, the study aims to identify early signs of cognitive decline before significant brain damage occurs. This could lead to timely interventions that may help preserve cognitive function in at-risk individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults with type 2 diabetes who are concerned about their cognitive health.
Not a fit: Patients without type 2 diabetes or those who are not in the older adult age group may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early identification and intervention strategies for older adults at risk of dementia due to diabetes.
How similar studies have performed: Previous studies have shown promising results in using advanced MRI techniques to assess brain health in similar populations, indicating that this approach may be effective.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BANGEN, KATHERINE — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: BANGEN, KATHERINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome