How depression in mothers affects brain development in children from different income backgrounds

Early brain development in children born to depressed mothers in high and low income settings

NIH-funded research University of Cape Town · NIH-10904874

This study looks at how a mother's depression can affect her child's brain development from birth to age 11, especially in families with different income levels, and aims to find ways to help children grow up healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Cape Town NIH-funded
Lab location1 site (Rondebosch, South Africa)
Project IDNIH-10904874 on NIH RePORTER

What this research studies

This research investigates the impact of maternal depression on the brain development of children aged 0-11 years, focusing on differences between high and low-income settings. By utilizing brain imaging techniques, the study aims to understand how economic factors influence the neurological outcomes in children born to depressed mothers. The research will collect and analyze data from various regions, particularly in Africa, to identify patterns and potential interventions. This approach seeks to provide insights into early childhood development and the role of socioeconomic status.

Who could benefit from this research

Good fit: Ideal candidates for participation are children aged 0-11 years whose mothers are experiencing depression, particularly in varying economic contexts.

Not a fit: Patients who do not have a mother with depression or are outside the specified age range may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved support and interventions for children affected by maternal depression, enhancing their developmental outcomes.

How similar studies have performed: Previous research has shown that maternal mental health significantly impacts child development, indicating that this study's approach is grounded in established findings.

Where this research is happening

Rondebosch, South Africa

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.