How decision-making changes in teens with bulimia nervosa

Charting the Development of Exploration in Adolescent Bulimia Nervosa: A Neurocomputational Approach

NIH-funded research Virginia Commonwealth University · NIH-11322036

This work uses games and brain scans to see how teenage girls with bulimia nervosa make exploratory versus impulsive choices over time.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-11322036 on NIH RePORTER

What this research studies

You would be invited to play a decision-making 'bandit' game while having a functional MRI to measure brain activity. The project will enroll three age cohorts of adolescent girls (early, middle, and late adolescence) with bulimia nervosa and matched peers, about 120 participants total. The team will use computer models to break down different exploration and impulsivity strategies and repeat the game and questionnaires remotely at 1- and 2-year follow-ups. The goal is to map how these decision patterns and their brain circuits change during adolescence to guide better-targeted care.

Who could benefit from this research

Good fit: Girls and young women aged about 12–20 with a diagnosis of bulimia nervosa (and matched healthy peers) are the ideal participants for this project.

Not a fit: People outside the 12–20 age range, those without bulimia nervosa, or those with unstable medical conditions are unlikely to gain direct benefit from participating.

Why it matters

Potential benefit: If successful, this work could point to specific decision-making processes and brain targets to improve treatments for adolescents with bulimia nervosa.

How similar studies have performed: Related decision-making and fMRI approaches have produced useful insights in other psychiatric conditions, but applying computational bandit tasks to adolescent bulimia nervosa is relatively new.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.