How decision-making changes as we age and with neurodegenerative diseases

Changes across the lifespan in the use of heuristics to guide decision-making

NIH-funded research University of Washington · NIH-10589139

This study looks at how people make decisions as they get older, especially focusing on older adults and those with conditions like Alzheimer's, to better understand how aging and cognitive challenges affect their thinking and choices.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10589139 on NIH RePORTER

What this research studies

This research investigates how decision-making processes evolve throughout a person's life, particularly focusing on older adults and those with neurodegenerative diseases like Alzheimer's. It aims to understand how aging affects the use of heuristics, or mental shortcuts, in making decisions. By developing a novel animal model, the researchers will explore the differences in decision-making abilities between younger and older individuals, as well as those with cognitive impairments. The findings could provide insights into the cognitive changes that occur with age and disease.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults, particularly those experiencing cognitive decline or diagnosed with Alzheimer's disease.

Not a fit: Patients who are younger and do not have any cognitive impairments or neurodegenerative diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for supporting decision-making in older adults and those with neurodegenerative diseases.

How similar studies have performed: Previous research has shown that cognitive processes related to decision-making can change with age and disease, suggesting that this area of study is both relevant and potentially impactful.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.