NIH-funded research R03 grant

How daily stress affects inflammation in older adults

Official title: Stress and Affective Mechanisms that Relate to Inflammation in Diverse Older Men and Women

Funded at South Dakota State University · NIH-10948644 · Data updated 2026-11-12

This study looks at how everyday stress affects inflammation in older adults, helping us understand how stress and emotions can impact health, and it will also see if there are differences between men and women in these effects.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionSouth Dakota State University
NIH-funded
Lab location1 site (Brookings, United States)
Project startSeptember 15, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$148,500
NIH project number1R03AG088758-01
Project IDNIH-10948644 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults aged 65 and above who experience daily stressors.

Less likely to help

Patients under the age of 65 or those not experiencing significant daily stressors may not benefit from this research.

What this research studies

This research investigates the relationship between daily stressors and inflammation in older adults, focusing on how stress and emotional reactions can influence health outcomes. By analyzing data from the Einstein Aging Study, the research aims to identify specific aspects of daily stress, such as frequency and severity, that are linked to increased inflammation. The study will also explore differences in these effects between men and women, providing insights into how stress impacts health in diverse populations of older adults.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of inflammation-related health issues in older adults.

How similar studies have gone: Previous research has shown promising results in understanding the link between stress and inflammation, but this study focuses specifically on older adults, making it a novel approach.

Where this research is happening

  • South Dakota State University
    Brookings, United States
    Active

Researchers

  • Principal investigator: Witzel, Dakota Danielle — South Dakota State University
  • Study coordinator: Witzel, Dakota Danielle

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.