How daily stress affects heart health in urban African American adults
Official title: Stress and Cardiovascular Risk Among Urban African American adults: A Multilevel, Mixed Methods Approach
Funded at Wayne State University · NIH-11373857 · Data updated 2026-11-12
Researchers will follow middle-aged and older African American adults in urban areas to link daily stress, emotions, and behaviors with heart disease risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project start | April 20, 2021 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $9,036 |
| NIH project number | 3R01HL153377-05S1 |
| Project ID | NIH-11373857 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are middle-aged and older African American adults who live in urban communities (often recruited in Detroit) and are willing to complete daily reports and provide biological samples.
✕Less likely to help
People who are not African American, who live outside urban settings, or who are outside the study's age focus are less likely to be represented and may not receive direct benefit.
What this research studies
You would report daily stressors and emotions during two separate waves of data collection spread over two years and complete surveys and interviews about your life and health behaviors. The project will collect biological samples to measure inflammation and stress-related hormones alongside the self-reported data. Researchers will combine interview findings, daily reports, and lab measures to map the psychological, behavioral, and biological pathways that may raise heart disease risk. The mixed-method approach is meant to capture both the situations you face day-to-day and how you respond to them.
Why it matters
Potential benefit: If successful, the work could reveal how everyday stress contributes to heart disease risk in African American adults and point to targets for prevention or tailored support.
How similar studies have gone: Previous research links stress and inflammation to heart disease risk, but few studies have used intensive daily mixed methods in urban African American adults, so this project is relatively novel.
Where this research is happening
-
Wayne State University
Detroit, United States Active
Researchers
- Principal investigator: Zilioli, Samuele — Wayne State University
- Study coordinator: Zilioli, Samuele
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.