How daily biological rhythms affect behavior in zebrafish
Circadian regulation of brain and body in larval zebrafish
This study looks at how the natural sleep and activity patterns of baby zebrafish affect their movements and health, helping us understand how problems with sleep can impact well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11093996 on NIH RePORTER |
What this research studies
This research investigates how circadian rhythms influence the behavior and physiology of larval zebrafish. By studying the interactions between neurons, muscles, and biomechanics, the researchers aim to understand how disruptions in sleep and activity cycles can lead to various health issues. The approach involves tracking zebrafish behavior and arousal throughout the day and manipulating light exposure to observe changes. This work utilizes genetic and physiological methods to explore the underlying mechanisms of circadian regulation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing sleep disturbances or related behavioral issues.
Not a fit: Patients with no sleep-related issues or those who do not have a biological basis for their behavioral conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment of sleep-related disorders and their impact on overall health.
How similar studies have performed: Other research has shown promising results in understanding circadian rhythms and their effects on behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Ehrlich, David Edward — University of Wisconsin-Madison
- Study coordinator: Ehrlich, David Edward
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.