NIH-funded research NIH-funded research

How cultural mismatch affects Latinx students' health and college success during the transition to university

Official title: Investigating Cultural Mismatch and its Associations to Health and Academic Outcomes Among Latinx Students During the Transition to College: The Moderating Role of Education Context and Resilience

Funded at California State University Northridge · NIH-11141623 · Data updated 2026-11-12

This project explores how differences between home and college values affect Latinx first-generation students' stress, physical health (like cortisol and BMI), and academic progress in their first year.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCalifornia State University Northridge
NIH-funded
Lab location1 site (Northridge, United States)
Project startAugust 15, 2022
Project endJune 30, 2026
Funding year2025
Award (this year)$181,250
NIH project number5R16GM146693-04
Project IDNIH-11141623 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are Latinx first-generation college freshmen at the participating public four-year universities who can complete surveys, an interview, and provide saliva and basic clinical measurements across three time points.

Less likely to help

Students who are not Latinx, not first-generation, not beginning their college transition, or unwilling/unable to provide biological samples are unlikely to be eligible or to directly benefit from this project.

What this research studies

You would join as a Latinx first-generation freshman at one of two public universities and complete surveys and an interview about your values, stress, and college experience. The team will collect biological samples (diurnal saliva for cortisol) and clinical measures (height/weight for BMI) at three time points: first semester, second semester, and one year later. Researchers will compare students at a teaching-centered versus a research-centered university and examine whether personal resilience and the school environment change the effects of cultural mismatch. The goal is to link cultural stress with both health markers and academic outcomes to guide supports for students.

Why it matters

Potential benefit: If successful, the findings could guide programs or supports that reduce stress, protect health, and improve retention and graduation for Latinx first-generation students.

How similar studies have gone: Prior qualitative, survey, and experimental work suggests cultural mismatch matters for Latinx students, but adding longitudinal biological markers and cross-campus comparison is a newer approach with limited precedent.

Where this research is happening

  • California State University Northridge
    Northridge, United States
    Active

Researchers

  • Principal investigator: Vasquez-Salgado, Yolanda — California State University Northridge
  • Study coordinator: Vasquez-Salgado, Yolanda

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.