How critical care affects cognitive and mental health in older adults
Neurovascular Contributions to Cognitive and Mental health in Older Adult Critical Care Survivors
['FUNDING_OTHER'] · SPAULDING REHABILITATION HOSPITAL · NIH-10702081
This study is looking at how being in the ICU affects the thinking and mental health of older adults over 60, especially those who might develop issues like Alzheimer's, and it aims to find new ways to spot these problems early so we can help them feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SPAULDING REHABILITATION HOSPITAL (nih funded) |
| Locations | 1 site (CHARLESTOWN, UNITED STATES) |
| Trial ID | NIH-10702081 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of Intensive Care Unit (ICU) hospitalization on the cognitive and mental health of older adults, particularly those over 60 years old. It focuses on identifying new biomarkers that can help diagnose and monitor conditions like Alzheimer's disease and related dementias in patients who may experience Post-Intensive Care Syndrome (PICS). The study aims to understand the relationship between chronic inflammation and cognitive decline in this vulnerable population, using advanced biological markers for better patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults over 60 who have recently been hospitalized in an ICU.
Not a fit: Patients under 60 years old or those who have not been admitted to an ICU may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management of cognitive impairments in older ICU survivors.
How similar studies have performed: Other research has shown promise in identifying biomarkers for cognitive decline in older adults, suggesting that this approach could yield valuable insights.
Where this research is happening
CHARLESTOWN, UNITED STATES
- SPAULDING REHABILITATION HOSPITAL — CHARLESTOWN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YATES, BRANDON — SPAULDING REHABILITATION HOSPITAL
- Study coordinator: YATES, BRANDON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's disease and related dementia, Alzheimer's disease and related disorders, Alzheimer's disease or a related dementia, Alzheimer's disease or a related disorder, Alzheimer's disease or related dementia