How critical care affects cognitive and mental health in older adults
Official title: Neurovascular Contributions to Cognitive and Mental health in Older Adult Critical Care Survivors
Funded at Spaulding Rehabilitation Hospital · NIH-10702081 · Data updated 2026-11-12
This study is looking at how being in the ICU affects the thinking and mental health of older adults over 60, especially those who might develop issues like Alzheimer's, and it aims to find new ways to spot these problems early so we can help them feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Spaulding Rehabilitation Hospital NIH-funded |
| Lab location | 1 site (Charlestown, United States) |
| Project start | September 1, 2021 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $91,152 |
| NIH project number | 8K00AG090127-03 |
| Project ID | NIH-10702081 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults over 60 who have recently been hospitalized in an ICU.
✕Less likely to help
Patients under 60 years old or those who have not been admitted to an ICU may not benefit from this research.
What this research studies
This research investigates the impact of Intensive Care Unit (ICU) hospitalization on the cognitive and mental health of older adults, particularly those over 60 years old. It focuses on identifying new biomarkers that can help diagnose and monitor conditions like Alzheimer's disease and related dementias in patients who may experience Post-Intensive Care Syndrome (PICS). The study aims to understand the relationship between chronic inflammation and cognitive decline in this vulnerable population, using advanced biological markers for better patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management of cognitive impairments in older ICU survivors.
How similar studies have gone: Other research has shown promise in identifying biomarkers for cognitive decline in older adults, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Spaulding Rehabilitation Hospital
Charlestown, United States Active
Researchers
- Principal investigator: Yates, Brandon — Spaulding Rehabilitation Hospital
- Study coordinator: Yates, Brandon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.