How COVID spreads in households and communities in low-resource countries

COVID Global Mix - Global Mix / Investigation of COVID-19 Disease Parameters for Transmission Models in Low-Resource Settings

['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11495175

This project measures how COVID-19 moves between people in homes and communities in low-resource countries to help shape better prevention and vaccination choices.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUT SOUTHWESTERN MEDICAL CENTER (nih funded)
Locations1 site (DALLAS, UNITED STATES)
Trial IDNIH-11495175 on ClinicalTrials.gov

What this research studies

If you join, the team will follow households over time in communities where GlobalMix works, asking people about their daily contacts and collecting respiratory (and sometimes blood) samples when someone gets sick. They will track who infects whom within households and combine that with detailed contact patterns from the community. That information will be used to build models that show how interventions like vaccines, masks, school closures, or stay-at-home actions could change spread. The work focuses on settings with limited resources so results better reflect local lives and conditions.

Who could benefit from this research

Good fit: Ideal participants are people living in the specific low-resource communities enrolled in the GlobalMix program, including households with children and adults willing to answer contact surveys and provide respiratory (and sometimes blood) samples over time.

Not a fit: People not living in the study communities or those seeking immediate treatment for their own illness are unlikely to gain direct personal benefit from participation.

Why it matters

Potential benefit: If successful, the findings could help design prevention and vaccination strategies that better protect people in low-resource communities.

How similar studies have performed: Previous household transmission and social-contact studies have informed public-health guidance, but combining longitudinal sampling with highly detailed contact data in low-resource settings is relatively new.

Where this research is happening

DALLAS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Airway infections

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.