How COVID-19 infection and vaccination may affect the risk of Alzheimer’s disease.
The Impact of SARS-CoV-2 Infection and Vaccination on the Risk of Alzheimer’s Disease and Related Dementias
This study is looking at how getting COVID-19 might affect your brain and increase the chances of developing Alzheimer’s or other types of dementia, and it will also explore how vaccines could help reduce these risks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11009489 on NIH RePORTER |
What this research studies
This research investigates the potential link between SARS-CoV-2 infection and the risk of developing Alzheimer’s disease and related dementias. It aims to understand how COVID-19 may cause neuroinflammation and other changes in the brain that could lead to cognitive decline. The study will utilize advanced epidemiological methods and longitudinal datasets to analyze the long-term effects of COVID-19 and the role of vaccinations in modifying these risks. Patients may be monitored through brain imaging and cognitive assessments over time to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults who have experienced COVID-19 infection or have received COVID-19 vaccinations.
Not a fit: Patients who have not been infected with SARS-CoV-2 or have not received vaccinations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for Alzheimer’s disease in individuals affected by COVID-19.
How similar studies have performed: While the link between infectious diseases and neurodegenerative conditions is being explored, this specific investigation into COVID-19's impact on Alzheimer’s disease is relatively novel.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Wang, Jingxuan — University of California, San Francisco
- Study coordinator: Wang, Jingxuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.