How COVID-19 affects recovery from diabetes and muscle metabolism

Impact of SARS CoV2 on post-hospital recovery of carbohydrate and muscle metabolism: role of endothelial injury

NIH-funded research University of Colorado Denver · NIH-10686353

This study is looking at how COVID-19 affects recovery for people with diabetes or high blood sugar, focusing on how it impacts their energy levels and muscle strength after being in the hospital.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-10686353 on NIH RePORTER

What this research studies

This research investigates how COVID-19 impacts recovery from hospitalization, particularly focusing on carbohydrate metabolism and muscle function in patients with pre-existing diabetes or those experiencing stress hyperglycemia. The study aims to understand the relationship between COVID-19-related endothelial injury and persistent high blood sugar levels, which may hinder recovery. By examining these factors, the research seeks to identify how they contribute to fatigue and other complications after infection. Patients will be monitored for changes in insulin secretion and action as they recover from COVID-19.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with pre-existing diabetes or those who have experienced hyperglycemia during or after a COVID-19 infection.

Not a fit: Patients without diabetes or those who have not experienced hyperglycemia related to COVID-19 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved recovery strategies for patients with diabetes who have been hospitalized due to COVID-19.

How similar studies have performed: Other research has indicated that COVID-19 can have significant effects on metabolic processes, suggesting that this study's approach is both relevant and necessary.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseasescardiovascular disorderDiabetes Mellitusdiabetes
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.