How COVID-19 affects people living with HIV/AIDS
Understanding Co-morbidities: COVID-19 in individuals living with HIV/AIDS
['FUNDING_R01'] · TEXAS BIOMEDICAL RESEARCH INSTITUTE · NIH-11019828
This study is looking at how COVID-19 affects people living with HIV/AIDS by using monkey models to see if having HIV makes COVID-19 worse, and it aims to understand the immune responses involved to help improve care for those affected.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEXAS BIOMEDICAL RESEARCH INSTITUTE (nih funded) |
| Locations | 1 site (SAN ANTONIO, UNITED STATES) |
| Trial ID | NIH-11019828 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of COVID-19 on individuals living with HIV/AIDS by utilizing rhesus macaque models to understand the relationship between SIV infection and the severity of COVID-19. The study aims to characterize how underlying HIV infection may lead to worse outcomes in COVID-19 cases, particularly focusing on both acute and post-acute effects. By examining the immune responses in these models, the research seeks to uncover the mechanisms that contribute to increased vulnerability in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV/AIDS who may be at risk for severe COVID-19 outcomes.
Not a fit: Patients who do not have HIV/AIDS or those who are not at risk for severe COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and preventive measures for people living with HIV/AIDS who contract COVID-19.
How similar studies have performed: Previous research has shown that understanding co-morbidities in infectious diseases can lead to significant advancements in treatment, indicating potential success for this approach.
Where this research is happening
SAN ANTONIO, UNITED STATES
- TEXAS BIOMEDICAL RESEARCH INSTITUTE — SAN ANTONIO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SINGH, DHIRAJ KUMAR — TEXAS BIOMEDICAL RESEARCH INSTITUTE
- Study coordinator: SINGH, DHIRAJ KUMAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus