How COVID-19 affects people living with HIV/AIDS
Official title: Understanding Co-morbidities: COVID-19 in individuals living with HIV/AIDS
Funded at Texas Biomedical Research Institute · NIH-11019828 · Data updated 2026-11-12
This study is looking at how COVID-19 affects people living with HIV/AIDS by using monkey models to see if having HIV makes COVID-19 worse, and it aims to understand the immune responses involved to help improve care for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Biomedical Research Institute NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | February 1, 2022 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $934,853 |
| NIH project number | 5R01AI170197-04 |
| Project ID | NIH-11019828 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV/AIDS who may be at risk for severe COVID-19 outcomes.
✕Less likely to help
Patients who do not have HIV/AIDS or those who are not at risk for severe COVID-19 may not benefit from this research.
What this research studies
This research investigates the impact of COVID-19 on individuals living with HIV/AIDS by utilizing rhesus macaque models to understand the relationship between SIV infection and the severity of COVID-19. The study aims to characterize how underlying HIV infection may lead to worse outcomes in COVID-19 cases, particularly focusing on both acute and post-acute effects. By examining the immune responses in these models, the research seeks to uncover the mechanisms that contribute to increased vulnerability in this population.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and preventive measures for people living with HIV/AIDS who contract COVID-19.
How similar studies have gone: Previous research has shown that understanding co-morbidities in infectious diseases can lead to significant advancements in treatment, indicating potential success for this approach.
Where this research is happening
-
Texas Biomedical Research Institute
San Antonio, United States Active
Researchers
- Principal investigator: Singh, Dhiraj Kumar — Texas Biomedical Research Institute
- Study coordinator: Singh, Dhiraj Kumar
Related research
Other NIH-funded projects on the same topics.
-
How COVID-19 affects people living with HIV
Researchers are using monkey models to find out whether having HIV changes how COVID-19 looks and how severe it can be for people with HIV.
-
An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya
A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.
-
FIOCRUZ HIV/AIDS Clinical Trials Unit: advancing HIV prevention and treatment in Brazil
A Brazilian clinical trials unit led by Dr. Beatriz Grinsztejn is testing and speeding up new HIV prevention and treatment strategies to help people living with HIV/AIDS and those at risk.
-
Breeding colony expansion to support HIV/AIDS research with rhesus macaques
A funding opportunity to expand a specialized Rhesus macaque breeding population to support HIV/AIDS research at Tulane’s primate facility.
-
HIV Resilience Observatory in a rhesus macaque colony expansion
A program to build a rhesus macaque breeding colony and use AI-powered monitoring to study why some HIV/AIDS outcomes differ among individuals with similar backgrounds.
-
Indoor-Outdoor Housing Expansion to Support HIV/AIDS-Related Research
A HIV-focused project at a primate research center will use new indoor/outdoor housing and AI-assisted monitoring to study why people with similar backgrounds can have very different HIV outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.