How cooling duration affects recovery in cardiac arrest patients

1/2 ICECAP: Influence of Cooling duration on Efficacy in Cardiac Arrest Patients

['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10915392

This study is looking at how different lengths of cooling after a cardiac arrest can help patients recover better, especially in terms of brain function, and it's for people who have been resuscitated from cardiac arrest.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-10915392 on ClinicalTrials.gov

What this research studies

This research investigates the impact of different cooling durations on the recovery of patients who have experienced cardiac arrest. It aims to determine whether longer periods of therapeutic cooling can lead to better neurological outcomes for patients who have been resuscitated from cardiac arrest. The study will involve randomized evaluations to assess the effectiveness of cooling in various patient scenarios, particularly those resuscitated from asystole and pulseless electrical activity. By analyzing these outcomes, the research seeks to establish optimal cooling protocols that could enhance patient recovery.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who have experienced out-of-hospital cardiac arrest and are in a comatose state post-resuscitation.

Not a fit: Patients who have not experienced cardiac arrest or those who are not in a comatose state after resuscitation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve recovery rates and neurological outcomes for cardiac arrest survivors.

How similar studies have performed: Previous studies have shown promise in using therapeutic cooling for cardiac arrest patients, but this specific approach to optimizing cooling duration is novel and has not been extensively tested.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.