How cooling duration affects recovery in cardiac arrest patients

2/2 ICECAP: Influence of Cooling duration on Efficacy in Cardiac Arrest Patients

['FUNDING_OTHER'] · MEDICAL UNIVERSITY OF SOUTH CAROLINA · NIH-10914761

This study is looking at how long to cool the brain after someone has had a cardiac arrest to help them recover better, especially for those who are in a coma after being resuscitated.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorMEDICAL UNIVERSITY OF SOUTH CAROLINA (nih funded)
Locations1 site (CHARLESTON, UNITED STATES)
Trial IDNIH-10914761 on ClinicalTrials.gov

What this research studies

This research investigates the impact of different cooling durations on the recovery of patients who have experienced cardiac arrest. It focuses on patients who are comatose after resuscitation, aiming to determine the optimal length of therapeutic cooling to protect the brain from injury. The study will involve randomized evaluations to assess outcomes in patients resuscitated from various cardiac rhythms, including those who may not typically benefit from cooling. By analyzing these factors, the research seeks to enhance recovery rates and neurological outcomes for survivors of cardiac arrest.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients who have experienced out-of-hospital cardiac arrest and are in a comatose state post-resuscitation.

Not a fit: Patients who have not experienced cardiac arrest or those who are not in a comatose state after resuscitation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve neurological recovery and survival rates for patients who have suffered cardiac arrest.

How similar studies have performed: Previous studies have shown promise in using therapeutic cooling for cardiac arrest patients, but this specific approach to optimizing cooling duration is novel and has not been extensively tested.

Where this research is happening

CHARLESTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.