How community improvements affect opioid misuse and overdose rates

The Impact of Community Infrastructure Reinvestment Programs on Opioid Misuse and Opioid Overdose

NIH-funded research University of Pennsylvania · NIH-10932970

This study looks at how fixing up neighborhoods, like cleaning vacant lots and repairing homes, can help reduce opioid misuse and overdose rates in struggling communities in Philadelphia, especially those with a lot of minority residents.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10932970 on NIH RePORTER

What this research studies

This research investigates how community infrastructure reinvestment programs, such as cleaning up vacant lots and repairing homes, can impact opioid misuse and overdose rates in neighborhoods affected by disinvestment and disorder. By focusing on resource-deprived, minority-majority neighborhoods in Philadelphia, the study aims to understand the relationship between neighborhood conditions and opioid-related issues. The approach includes partnerships between government, community organizations, and academic institutions to implement structural interventions and assess their effects on opioid misuse behaviors and overdose risks.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living in neighborhoods with high levels of opioid misuse and associated social challenges, particularly in resource-deprived areas.

Not a fit: Patients living in areas with stable community infrastructure and low rates of opioid misuse may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective community interventions that reduce opioid misuse and overdose rates, ultimately improving public health outcomes.

How similar studies have performed: Previous studies in Philadelphia have shown that community interventions can reduce crime and improve mental health, suggesting potential for success in addressing opioid misuse as well.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.