How cold affects the sense of touch in animals
Molecular mechanisms of somatosensory adaptation to prolonged hypothermia
['FUNDING_R01'] · YALE UNIVERSITY · NIH-11003742
This study looks at how thirteen-lined ground squirrels can still feel touch even when they get really cold, and by learning about their unique abilities, researchers hope to find new ways to help people with touch-related issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11003742 on ClinicalTrials.gov |
What this research studies
This research investigates how the sense of touch adapts in animals, specifically focusing on the thirteen-lined ground squirrel during periods of prolonged cold. By studying these squirrels, which can still detect mechanical stimuli even when their body temperature drops significantly, the researchers aim to uncover the molecular and cellular mechanisms that allow for this adaptation. The approach involves biophysical analysis of the sensory receptors responsible for mechanosensitivity, providing insights into how these processes function under extreme conditions. This understanding could lead to advancements in treating sensory dysfunctions in humans.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with sensory processing disorders or those who have experienced nerve damage.
Not a fit: Patients with conditions unrelated to sensory dysfunction or those not experiencing any sensory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for sensory dysfunctions in humans, improving quality of life for those affected.
How similar studies have performed: While the specific approach of studying hibernating squirrels is novel, similar research has shown that understanding animal adaptations can lead to breakthroughs in human medicine.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAGRIANTSEV, SVIATOSLAV — YALE UNIVERSITY
- Study coordinator: BAGRIANTSEV, SVIATOSLAV
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.