How cockroaches spread Salmonella bacteria

Biological vector borne transmission of Salmonella by cockroaches

NIH-funded research Purdue University · NIH-11223318

Researchers are looking at how German cockroaches pick up and shed Salmonella so people can better prevent foodborne illness.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPurdue University NIH-funded
Lab location1 site (West Lafayette, United States)
Project IDNIH-11223318 on NIH RePORTER

What this research studies

From my perspective, this work uses lab experiments with German cockroaches and Salmonella bacteria to see whether the bugs can harbor and multiply the germs in their guts rather than just carrying them on their bodies. Scientists will track how long infected cockroaches shed Salmonella, identify bacterial genes needed to colonize the insect gut, and study the insect gut environment that helps bacteria survive. The team combines microbiology, insect biology, and genetic techniques to map the steps that lead to active transmission. Results aim to point toward ways to reduce contamination in homes, food facilities, and other places where cockroaches and people overlap.

Who could benefit from this research

Good fit: People living or working in places with known cockroach infestations or communities with repeated Salmonella outbreaks would be most relevant to the findings and possible future participation.

Not a fit: Anyone without exposure to cockroaches or with infections unrelated to enteric (gut) bacteria is unlikely to receive direct benefit from this research.

Why it matters

Potential benefit: If successful, this work could lead to better prevention strategies and pest-control approaches that lower the risk of Salmonella outbreaks linked to cockroaches.

How similar studies have performed: Earlier work mostly treated cockroach spread as passive transfer, but recent laboratory results — including from this team — suggest active colonization and shedding can occur, so this builds on emerging but still limited evidence.

Where this research is happening

West Lafayette, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.