How classroom microbes affect asthma in children

The school microbiome and asthma morbidity in inner-city children

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10541838

This study is looking at how the tiny living things in classrooms can affect asthma symptoms in kids, and it aims to find ways to make school environments healthier for children with asthma.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10541838 on ClinicalTrials.gov

What this research studies

This research investigates the role of the indoor microbiome in classrooms and its impact on asthma symptoms in children. By examining how microbial diversity in school environments can influence asthma morbidity, the study aims to identify ways to create healthier indoor spaces for children with asthma. The research utilizes a randomized controlled trial approach, leveraging existing interventions to modify the classroom microbiome and assess its effects on asthma outcomes. The ultimate goal is to reduce asthma symptoms through environmental changes in schools.

Who could benefit from this research

Good fit: Ideal candidates for this research are children diagnosed with asthma who attend inner-city schools.

Not a fit: Patients without asthma or those who do not attend participating schools may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved asthma management and reduced symptoms for children in urban school settings.

How similar studies have performed: Previous studies have shown promising results in modifying environmental factors to improve asthma outcomes, suggesting this approach may be effective.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.