How chronic stress affects metabolism differently in males and females
Sex differences and metabolic responses to chronic stress
This study looks at how long-term stress affects metabolism in male and female rats, aiming to learn more about the brain's role in these responses, which could help us find better ways to manage stress-related health issues.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project ID | NIH-10863971 on NIH RePORTER |
What this research studies
This research investigates the impact of chronic stress on metabolic health, focusing on how male and female rats respond differently to stress. The study aims to understand the neural mechanisms that influence these responses, particularly the role of specific brain circuits in regulating stress-related endocrine and metabolic changes. By examining the activation of the infralimbic cortex and its connection to the rostral ventrolateral medulla, the research seeks to uncover insights that could lead to better management of stress-related metabolic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research would be individuals experiencing chronic stress and related metabolic issues, particularly those interested in understanding sex-specific responses.
Not a fit: Patients who do not experience chronic stress or metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for metabolic disorders influenced by stress, tailored to the specific needs of different sexes.
How similar studies have performed: Previous research has shown that understanding sex differences in stress responses can lead to significant advancements in treatment strategies, indicating that this approach has potential for success.
Where this research is happening
Fort Collins, United States
- Colorado State University — Fort Collins, United States (Active)
Researchers
- Principal investigator: Dearing, Carley — Colorado State University
- Study coordinator: Dearing, Carley
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.