How chronic stress affects cancer treatment and immune response to radiation therapy
The impact of chronic stress on radiation induced cell death and the anti-tumor immune response
This study is looking at how long-term stress might make radiation therapy less effective for cancer patients, and it aims to find ways to improve treatment by understanding how stress affects the body’s ability to fight cancer.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Roswell Park Cancer Institute Corp NIH-funded |
| Lab location | 1 site (Buffalo, United States) |
| Project ID | NIH-10918276 on NIH RePORTER |
What this research studies
This research investigates the effects of chronic stress on the effectiveness of radiation therapy in cancer treatment. It focuses on how stress can hinder tumor cell death and weaken the immune response that is crucial for fighting cancer. By examining the mechanisms behind this stress-induced resistance, the study aims to identify ways to enhance the effectiveness of radiation therapy for cancer patients. The research involves both laboratory experiments and in vivo studies to understand the relationship between stress and cancer treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients undergoing radiation therapy who may be experiencing chronic stress.
Not a fit: Patients who are not undergoing radiation therapy or those without chronic stress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved radiation therapy strategies that enhance tumor cell death and boost the immune response in cancer patients.
How similar studies have performed: Other research has shown that addressing stress can improve cancer treatment outcomes, suggesting that this approach may yield significant insights.
Where this research is happening
Buffalo, United States
- Roswell Park Cancer Institute Corp — Buffalo, United States (Active)
Researchers
- Principal investigator: Macdonald, Cameron Riker — Roswell Park Cancer Institute Corp
- Study coordinator: Macdonald, Cameron Riker
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.