How cholera spreads across Africa
Epidemiology and Ecology of Cholera in Africa
This project follows cholera bacteria and the viruses that affect them in African communities to help stop outbreaks and protect people at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11308281 on NIH RePORTER |
What this research studies
From your point of view, researchers collect samples and case information in places that regularly get cholera, focusing on Nigeria and Uganda. They use genetic tests and mapping tools to track which strains of Vibrio cholerae and related bacteriophages move between districts. The team also monitors how water, sanitation, and hygiene interventions change transmission. Findings will feed a "cholera elimination scorecard" to show progress toward stopping cholera in specific districts.
Who could benefit from this research
Good fit: Ideal participants are people living in cholera-affected districts who can provide clinical information or biological samples for surveillance in Nigeria, Uganda, or other endemic areas.
Not a fit: People who live outside the study regions or who are not exposed to cholera are unlikely to get direct benefits from this project.
Why it matters
Potential benefit: If successful, this work could help health officials stop cholera spread faster and reduce the number of people who get sick.
How similar studies have performed: Similar molecular and mapping approaches have been used successfully before and this project builds on earlier findings that tracked cholera lineages across Africa.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Sack, David a — Johns Hopkins University
- Study coordinator: Sack, David a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.