How childhood maltreatment affects disease risk in young adults through stress regulation
Childhood Maltreatment and Disease Risk in Young Adulthood: The Role of HPA Regulation in Adolescence
This study is looking at how experiencing tough times as a child can affect your health as a young adult, especially by changing how your body handles stress, and it’s for anyone interested in understanding the long-term effects of childhood challenges on health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project ID | NIH-10848422 on NIH RePORTER |
What this research studies
This research investigates the long-term health impacts of childhood maltreatment, focusing on how it influences disease risk in young adulthood through the regulation of the body's stress response system, specifically the HPA axis. By examining the connections between maltreatment, stress regulation, and disease outcomes, the study aims to identify critical pathways that could lead to preventive measures. The research will utilize innovative modeling techniques to assess HPA axis functioning over time, from childhood through young adulthood, providing a comprehensive view of how early trauma can shape health trajectories. Participants will be involved in assessments that track their health and stress responses throughout this developmental period.
Who could benefit from this research
Good fit: Ideal candidates for this research include young adults who have a history of childhood maltreatment and are currently experiencing health issues related to stress or chronic diseases.
Not a fit: Patients who have not experienced childhood maltreatment or those who are not currently in the young adult age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies and interventions for individuals who experienced childhood maltreatment, ultimately reducing their risk of chronic diseases.
How similar studies have performed: Previous research has shown significant associations between childhood maltreatment and health outcomes, but this study aims to provide a novel approach by integrating HPA axis functioning over time.
Where this research is happening
Oakland, UNITED STATES
- Kaiser Foundation Research Institute — Oakland, United States (Active)
Researchers
- Principal investigator: Negriff, Sonya L — Kaiser Foundation Research Institute
- Study coordinator: Negriff, Sonya L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.