How childhood immune development affects vaccine response and asthma risk
Proteomics and Metabolomics Core: IDEAL shapes vaccine response, susceptibility to respiratory infectious disease and asthma
This study is looking at how children's immune systems grow and change in their early years, and how this affects their reactions to vaccines, chances of getting respiratory infections, and risk of asthma, so we can find ways to help kids stay healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11051830 on NIH RePORTER |
What this research studies
This research investigates how the immune system develops in early childhood and how this affects responses to vaccines, susceptibility to respiratory infections, and the risk of developing asthma. By analyzing biological markers and immune responses in children, the study aims to identify specific immune profiles that may indicate a higher risk for these conditions. The approach involves collecting and analyzing blood samples to create detailed molecular maps of immune development. This information could help in identifying children who may benefit from targeted interventions to improve their health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0 to 11 years, particularly those with a history of respiratory infections or asthma.
Not a fit: Patients outside the age range of 0 to 11 years or those without respiratory issues or asthma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification of children at risk for poor vaccine responses and asthma, allowing for earlier interventions.
How similar studies have performed: Previous research has shown promise in understanding immune development and its impact on health, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Steen, Hanno — Boston Children's Hospital
- Study coordinator: Steen, Hanno
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.