How childhood adversity affects stress responses in adolescents

The Impact of Adversity on Neurobiological and Psychosocial Dimensions of the Stress Response System

NIH-funded research Vanderbilt University Medical Center · NIH-11062503

This study looks at how tough experiences in childhood affect how teenagers handle stress, helping us understand their feelings and reactions better so we can find ways to support their mental health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11062503 on NIH RePORTER

What this research studies

This research investigates how experiences of childhood adversity impact the neurobiological and psychosocial aspects of stress responses in adolescents aged 12 to 20. By examining the physiological and emotional reactions to stress, the study aims to identify common mechanisms that contribute to mental health issues in those who have faced adversity. The approach includes assessing emotional reactivity, regulation, and flexibility in stress responses, which could lead to better understanding and treatment options for affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who have experienced significant childhood adversity.

Not a fit: Patients who have not experienced childhood adversity or are outside the age range of 12 to 20 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for adolescents who have experienced childhood adversity, enhancing their mental health outcomes.

How similar studies have performed: Previous research has shown that understanding the impact of childhood adversity on stress responses can lead to significant advancements in mental health treatment, indicating that this approach has potential for success.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.