How childhood adversity affects stress responses and emotional health
Visceral neural circuits linking childhood threat and deprivation with stress physiology and affective symptoms in a transdiagnostic sample using high-field personalized brain mapping
This study is looking at how tough experiences in childhood, like abuse or neglect, can affect how our bodies handle stress and our feelings later in life, and it’s for anyone interested in understanding the connection between early life challenges and mental health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10665711 on NIH RePORTER |
What this research studies
This research investigates the impact of childhood adversity, such as abuse and deprivation, on stress physiology and emotional symptoms in individuals. By using advanced brain mapping techniques, the study aims to identify specific neural circuits that are affected by these early life experiences. Participants will undergo assessments that link their childhood experiences to current stress responses and mood disorders, providing insights into how these factors interact. The goal is to better understand the biological mechanisms that underlie the relationship between childhood adversity and mental health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced childhood adversity, such as abuse or significant deprivation, and are currently facing mood or anxiety disorders.
Not a fit: Patients who have not experienced any form of childhood adversity or do not have related mental health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved interventions for individuals affected by childhood adversity, enhancing their mental health and stress management.
How similar studies have performed: Other research has shown promising results in linking childhood adversity to mental health outcomes, but this specific approach using high-field brain mapping is relatively novel.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Banihashemi, Layla — University of Pittsburgh at Pittsburgh
- Study coordinator: Banihashemi, Layla
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.