NIH-funded research P01 program project

How changing oceans are affecting toxins in shellfish

Official title: Changing Oceans Affect Shellfish Toxins

Funded at Sitka Tribe of Alaska · NIH-11387540 · Data updated 2026-11-12

This project predicts when and where Alaska shellfish will carry dangerous paralytic toxins so coastal and tribal communities can harvest more safely.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionSitka Tribe of Alaska
NIH-funded
Lab location1 site (Sitka, United States)
Project startMarch 20, 2024
Project endFebruary 28, 2029
Funding year2026
Award (this year)$129,638
NIH project number5P01ES035551-03
Project IDNIH-11387540 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are coastal Alaska community members, especially Alaska Native shellfish harvesters, who can contribute local observations, samples, or traditional knowledge.

Less likely to help

People who do not eat or collect local shellfish or who live far from affected Alaska coasts are unlikely to benefit directly.

What this research studies

Researchers are working with Southeast Alaska Tribal Ocean Research and local tribal partners to combine thousands of shellfish test results, environmental sensor data, satellite measurements, and traditional ecological knowledge. They will use machine learning and statistical models alongside lab analyses of specific toxin types to track how warming and ocean acidification change toxin production by Alexandrium algae. The team will map seasonal and location-specific patterns and develop forecasts of high-risk harvest periods. Findings will be shared with coastal communities to improve warnings and guidance for subsistence shellfish harvesters.

Why it matters

Potential benefit: If successful, the work could provide clearer forecasts and guidance to help people avoid paralytic shellfish poisoning.

How similar studies have gone: Local and tribal monitoring programs have successfully detected harmful algal blooms before, but combining long-term community data with machine learning and congener-specific toxin analysis is a newer, less-tested approach.

Where this research is happening

  • Sitka Tribe of Alaska
    Sitka, United States
    Active

Researchers

  • Principal investigator: Harley, John — Sitka Tribe of Alaska
  • Study coordinator: Harley, John

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.