How changing contraceptive methods affect ovarian cancer risk
Changing Contraceptive Patterns and Ovarian Cancer Risk
['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11075136
This study is looking at how changes in birth control methods, like fewer people using the pill and more using IUDs, might affect the risk of ovarian cancer, especially how different IUDs could influence this risk, so it’s for anyone interested in understanding how their contraceptive choices might relate to their health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11075136 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between changing contraceptive patterns, specifically the decline in oral contraceptive use and the rise of intrauterine devices (IUDs), and their impact on ovarian cancer risk. It aims to understand how different types of IUDs may influence the incidence of various ovarian cancer subtypes, particularly in relation to inflammation and immune response. By analyzing data from the New England Case Control Study, the research seeks to clarify the potential protective effects of contraceptives against ovarian cancer and identify any associated risks. The study will involve larger sample sizes to ensure robust findings and better understanding of these associations.
Who could benefit from this research
Good fit: Ideal candidates for this research include women, particularly African American females, who are using or considering different contraceptive methods.
Not a fit: Patients who are not using contraceptives or those with a history of ovarian cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide insights into how contraceptive choices may influence ovarian cancer risk, potentially guiding safer contraceptive practices.
How similar studies have performed: Previous studies have suggested varying associations between IUD use and ovarian cancer risk, indicating that this research is building on existing knowledge but exploring new dimensions.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TERRY, KATHRYN L. — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: TERRY, KATHRYN L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.