NIH-funded research R01 grant

How changes in sleep and activity patterns affect heart health in teens and young adults

Official title: Circadian disruption and cardiometabolic risk during the transition from adolescence to young adulthood

Funded at University of Michigan at Ann Arbor · NIH-11046769 · Data updated 2026-11-12

This study is looking at how changes in sleep and daily routines during the teenage years can affect heart and overall health, and it's for young people who want to understand how their habits might impact their well-being as they grow up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startMay 1, 2025
Project endFebruary 28, 2030
Funding year2025
Award (this year)$691,124
NIH project number1R01HL169893-01A1
Project IDNIH-11046769 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents and young adults aged 12 to 20 who may experience irregular sleep patterns or have concerns about their heart health.

Less likely to help

Patients outside the age range of 12 to 20 or those without any circadian rhythm disruptions may not benefit from this research.

What this research studies

This research investigates how disruptions in circadian rhythms during the transition from adolescence to young adulthood can impact heart and metabolic health. It focuses on understanding the relationship between irregular sleep patterns, eating habits, and physical activity, and how these factors may lead to increased risks of cardiometabolic diseases. The study will analyze various biological markers and consider factors such as sex and sleep disorders to provide a comprehensive view of how these disruptions affect health outcomes. Participants will be monitored over time to assess changes in their health as they navigate this critical developmental period.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cardiometabolic diseases in adolescents and young adults.

How similar studies have gone: Previous research has shown promising results linking circadian rhythm disruptions to health issues, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Jansen, Erica Christine — University of Michigan at Ann Arbor
  • Study coordinator: Jansen, Erica Christine

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.