How changes in sex hormones affect pain after surgery

Examination of sex hormone alteration on post-operative pain development and treatment

NIH-funded research Texas Tech University Health Scis Center · NIH-10914920

This study is looking at how changes in sex hormones might affect the way people feel pain after surgery, especially for those who have different hormone levels, to help improve pain management for everyone.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTexas Tech University Health Scis Center NIH-funded
Lab location1 site (Lubbock, United States)
Project IDNIH-10914920 on NIH RePORTER

What this research studies

This research investigates the impact of altered sex hormone levels on the development of chronic pain following surgical procedures. By using preclinical models, the study aims to understand how these hormonal changes may influence pain sensitivity and recovery in patients. The researchers will explore genetic and genomic mechanisms that could explain why some individuals experience more severe postoperative pain. This work is particularly focused on patients with altered sex hormone levels, which are often overlooked in pain management studies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have undergone surgery and have altered sex hormone levels.

Not a fit: Patients who have not undergone surgery or do not have any hormonal alterations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies for patients undergoing surgery, particularly those with hormonal imbalances.

How similar studies have performed: While the specific approach of examining sex hormone alterations in postoperative pain is relatively novel, there is existing research indicating that hormonal factors can influence pain perception and recovery.

Where this research is happening

Lubbock, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.