How changes in lung blood vessels affect heart failure in older adults
Contributions of pulmonary arterial and venous remodeling to HFpEF in the elderly
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11196078
This study is looking at how changes in the blood vessels in the lungs might affect heart failure in older adults, using special imaging to see these changes, with the hope of finding better ways to understand and treat this condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11196078 on ClinicalTrials.gov |
What this research studies
This research investigates how remodeling of the pulmonary arteries and veins contributes to heart failure with preserved ejection fraction (HFpEF) in elderly patients. The team uses advanced imaging techniques to analyze changes in lung blood vessels through non-contrast chest CT scans. By studying a community-based group of older adults, the research aims to uncover the relationship between pulmonary vascular changes and heart failure outcomes. The findings could lead to better understanding and potential new treatments for HFpEF.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals experiencing symptoms of heart failure, particularly those with preserved left ventricular function.
Not a fit: Patients who are younger or do not have heart failure or related symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for heart failure in older adults, enhancing their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding pulmonary vascular dysfunction in heart failure, suggesting that this approach could yield valuable insights.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHAH, AMIL M — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: SHAH, AMIL M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.