How certain immune cells help fight viral infections
Mechanisms of iNKT cell anti-viral adjuvancy
This study is looking at how a special type of immune cell called iNKT cells can help your body fight off viral infections better, especially in the case of Epstein-Barr virus, with the hope of finding new ways to improve treatment for viral infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10456109 on NIH RePORTER |
What this research studies
This research investigates the role of invariant natural killer T (iNKT) cells in enhancing the immune response against viral infections. iNKT cells are a type of immune cell that can boost the activity of other lymphocytes, particularly T cells, which are crucial for fighting viruses. The study aims to understand the mechanisms by which iNKT cells act as 'cellular adjuvants' to promote stronger anti-viral responses, using a model of Epstein-Barr virus infection. By exploring these mechanisms, the research seeks to develop new therapeutic strategies that could harness iNKT cells to improve viral infection outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with viral infections, particularly those affected by Epstein-Barr virus or similar conditions.
Not a fit: Patients with non-viral infections or those who do not have a functioning immune system may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance the body's ability to fight viral infections more effectively.
How similar studies have performed: Previous research has shown promise in utilizing immune cells like iNKT cells for enhancing anti-viral responses, indicating a potential for success in this approach.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Gumperz, Jenny E. — University of Wisconsin-Madison
- Study coordinator: Gumperz, Jenny E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.