How certain DNA elements affect aging and Alzheimer's disease

Who could benefit from this research

What this research studies

This research investigates the role of transposable elements, particularly human endogenous retroviruses, in the processes of healthy aging and Alzheimer's disease. By analyzing RNA sequencing data, the study aims to identify patterns of gene expression related to these elements in different brain regions and cell types. The researchers are also exploring the impact of specific signaling pathways on neurodegeneration using a mouse model. This approach could provide insights into the molecular mechanisms underlying aging and Alzheimer's disease.

Why it matters

Where this research is happening

• Feinstein Institute for Medical Research
  Manhasset, United States Active

Researchers

• Principal investigator: Nixon, Douglas F — Feinstein Institute for Medical Research
• Study coordinator: Nixon, Douglas F

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.