NIH-funded research R01 grant

How certain bacteria help clean up toxic pollutants

Official title: Mechanism of extracellular electron transfer in Gram-negative bacteria

Funded at Cornell University · NIH-10933727 · Data updated 2026-11-12

This study is exploring how a type of bacteria called Shewanella can help clean up harmful pollutants like heavy metals by figuring out how they transfer electrons, which could make our efforts to clean up polluted areas even better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCornell University
NIH-funded
Lab location1 site (Ithaca, United States)
Project startSeptember 1, 2024
Project endJune 30, 2028
Funding year2024
Award (this year)$329,615
NIH project number1R01GM154669-01
Project IDNIH-10933727 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living in communities affected by pollution from heavy metals and organic contaminants.

Less likely to help

Patients who are not in areas impacted by toxic pollutants may not receive direct benefits from this research.

What this research studies

This research investigates how Gram-negative bacteria, specifically Shewanella, can be used to degrade and detoxify harmful pollutants like heavy metals and organic compounds. By understanding the mechanism of extracellular electron transfer (EET) in these bacteria, the research aims to enhance bioremediation techniques, which are environmentally sustainable methods for cleaning polluted sites. The study focuses on the proteins involved in EET and how they work together to facilitate the transfer of electrons, which is crucial for the bacteria's ability to reduce toxins. This knowledge could lead to improved applications of these bacteria in environmental cleanup efforts.

Why it matters

Potential benefit: If successful, this research could lead to more effective and sustainable methods for cleaning up contaminated environments, benefiting public health and ecosystems.

How similar studies have gone: Previous research has shown promise in using bacteria for bioremediation, indicating that this approach has potential for success.

Where this research is happening

  • Cornell University
    Ithaca, United States
    Active

Researchers

  • Principal investigator: Chen, Peng — Cornell University
  • Study coordinator: Chen, Peng

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.