How cellular balance affects blood vessel growth
Cellular Reductive State Regulates Arteriogenesis
This study is looking at how the levels of natural antioxidants in our cells can help grow new blood vessels, especially when blood flow is limited, like in peripheral artery disease, to find better ways to improve blood flow and health for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project ID | NIH-10541130 on NIH RePORTER |
What this research studies
This research investigates the role of cellular antioxidant levels in the growth of blood vessels, particularly in conditions where blood flow is restricted, such as peripheral artery disease. By examining how changes in the balance of antioxidants influence signaling pathways that promote blood vessel formation, the study aims to understand the mechanisms behind vascular health. The research involves both laboratory experiments and animal models to explore how restoring a healthy cellular environment can improve blood flow and tissue health. Patients may benefit from insights that could lead to new treatments for cardiovascular diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from peripheral artery disease or other conditions characterized by restricted blood flow.
Not a fit: Patients with non-cardiovascular conditions or those not experiencing issues related to blood flow may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance blood vessel growth and improve blood flow in patients with cardiovascular diseases.
How similar studies have performed: Previous research has shown promising results in understanding the role of antioxidants in vascular health, suggesting that this approach could yield significant insights.
Where this research is happening
Shreveport, United States
- Louisiana State Univ Hsc Shreveport — Shreveport, United States (Active)
Researchers
- Principal investigator: Pattillo, Christopher Bruce — Louisiana State Univ Hsc Shreveport
- Study coordinator: Pattillo, Christopher Bruce
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.