How cells sense glucose using yeast receptors
Receptor-mediated glucose sensing in yeast
Using yeast, researchers aim to learn how glucose-sensing receptors work to ultimately help people with diabetes and obesity.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia International University NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project ID | NIH-11309760 on NIH RePORTER |
What this research studies
As someone concerned about diabetes, it helps to know researchers are using yeast cells to watch glucose receptors in action with a fluorescent microscope. They will measure sugar uptake with a fluorescent tracer, extract receptor proteins for biochemical tests, and use qRT-PCR to read gene activity linked to the receptors Rgt2 and Snf3. The project buys key lab equipment to speed up and improve these experiments. Results may reveal signaling steps that relate to human metabolic disease.
Who could benefit from this research
Good fit: This project is lab-based and does not enroll patients, so no one can participate directly.
Not a fit: People seeking immediate new treatments or clinical care changes are unlikely to benefit from this basic yeast research in the short term.
Why it matters
Potential benefit: If successful, this work could reveal molecular steps in glucose sensing that point to new treatment targets or diagnostic ideas for diabetes.
How similar studies have performed: Yeast and molecular studies have a long history of revealing basic pathways relevant to human metabolism, though translating those findings into treatments often takes time.
Where this research is happening
Columbia, United States
- Columbia International University — Columbia, United States (Active)
Researchers
- Principal investigator: Kim, Jeong-Ho — Columbia International University
- Study coordinator: Kim, Jeong-Ho
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.