How cells move during nervous system development
Biomechanics of Tissue Motility
['FUNDING_R01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-10877770
This study is looking at how cells move around during the development of the nervous system, using zebrafish to learn more about how they push and pull themselves forward, which could help us understand important processes in living organisms.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10877770 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which cells and tissues migrate during the development of the nervous system. Using zebrafish as a model organism, the study aims to understand how cells generate and transmit force to move forward. The researchers will employ advanced imaging techniques and a novel protein depletion method to observe these processes in real-time. By examining the role of specific proteins and cellular structures, the research seeks to uncover the fundamental principles of cellular motility in a living organism.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to developmental nervous system defects or those interested in the underlying mechanisms of cell movement.
Not a fit: Patients with fully developed nervous systems and no related conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment of developmental nervous system defects.
How similar studies have performed: Previous research has shown success in understanding cellular motility through similar approaches, particularly in model organisms like zebrafish.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KNAUT, HOLGER — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: KNAUT, HOLGER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.