How cells manage energy production and mitochondrial function
Metabolic Regulation of Mitochondrial Function
This study looks at how cells manage their energy production, especially focusing on mitochondria, which are like tiny power plants in our cells, and how they adapt based on the nutrients available; this research could help us understand better how these processes relate to diseases like cancer and immune disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11100250 on NIH RePORTER |
What this research studies
This research investigates how cells monitor and adjust their energy production based on metabolic needs, focusing on the role of mitochondria in generating ATP, the energy currency of cells. It explores how nutrient availability affects mitochondrial function and positioning, which is crucial for processes like cell migration, tumor invasion, and immune responses. By examining specific molecular pathways and post-translational modifications, the research aims to uncover the intricate relationships between metabolism and mitochondrial activity, potentially leading to new insights into various diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with metabolic disorders, cancer patients, or those experiencing issues related to energy metabolism.
Not a fit: Patients with conditions unrelated to metabolic regulation or mitochondrial dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for conditions related to energy metabolism, including certain cancers and metabolic disorders.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial function and its implications in various diseases, indicating that this approach has potential for significant advancements.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Pekkurnaz, Gulcin — University of California, San Diego
- Study coordinator: Pekkurnaz, Gulcin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.