How cells control their shape and division
Molecular mechanisms that control polarity and asymmetric cell division
This study is looking at how certain proteins help animal cells keep their different jobs by organizing their outer surfaces, which is especially important for tissues like the digestive system and brain, and it aims to help us understand how cells work together in our bodies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oregon NIH-funded |
| Lab location | 1 site (Eugene, United States) |
| Project ID | NIH-11076355 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms that allow animal cells to maintain different functions at distinct areas of their membranes. By focusing on the Par complex, a group of proteins, the study aims to understand how these proteins help create and maintain the asymmetry necessary for proper cell function, particularly in tissues like the digestive tract and brain. The research will explore how these cellular asymmetries contribute to the organization of tissues and the differentiation of various cell types. This work could provide insights into how cells communicate and function effectively within complex biological systems.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cellular dysfunction, such as certain cancers or gastrointestinal disorders.
Not a fit: Patients with non-cellular related conditions or those not experiencing issues with cell division or differentiation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to advancements in understanding and treating diseases related to cell division and differentiation, such as cancers.
How similar studies have performed: Other research has shown success in understanding cellular asymmetries and their implications in various diseases, indicating that this approach is grounded in established scientific principles.
Where this research is happening
Eugene, United States
- University of Oregon — Eugene, United States (Active)
Researchers
- Principal investigator: Prehoda, Kenneth E — University of Oregon
- Study coordinator: Prehoda, Kenneth E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.