How cells communicate through fluid flows
Cell-cell communication mediated by fluid flows
['FUNDING_OTHER'] · UNIVERSITY OF OREGON · NIH-11089542
This study is looking at how cells in zebrafish embryos sense and react to the movement of fluids around them, which is important for things like how organs develop and how cancer spreads, to help us understand how these signals influence cell behavior and gene activity.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF OREGON (nih funded) |
| Locations | 1 site (EUGENE, UNITED STATES) |
| Trial ID | NIH-11089542 on ClinicalTrials.gov |
What this research studies
This research investigates how cells detect and respond to fluid flows that occur around them, which is important for processes like organ development and cancer spread. By using zebrafish embryos, the researchers will explore the mechanisms of cell communication through these flows, focusing on specific proteins that play a role in sensing these signals. The study aims to uncover how these signals affect gene expression and cellular behavior, providing insights into fundamental biological processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by cancers or conditions related to cell signaling and communication.
Not a fit: Patients with conditions unrelated to cell signaling or fluid dynamics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating cancers and other diseases by targeting cell communication pathways.
How similar studies have performed: While the specific approach of studying fluid flow communication in cells is novel, related research in cell signaling has shown promising results in understanding cellular interactions.
Where this research is happening
EUGENE, UNITED STATES
- UNIVERSITY OF OREGON — EUGENE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GRIMES, DANIEL T — UNIVERSITY OF OREGON
- Study coordinator: GRIMES, DANIEL T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers