How cells change during early development
Intracellular Remodeling during Early Development
['FUNDING_OTHER'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-11011076
This study looks at how cells change when an egg turns into an embryo, focusing on important parts of the cell that help determine how the embryo develops, which is key for healthy reproduction.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded) |
| Locations | 1 site (CHAMPAIGN, UNITED STATES) |
| Trial ID | NIH-11011076 on ClinicalTrials.gov |
What this research studies
This research investigates the changes that occur in cellular machinery and organelles during the early stages of development, particularly focusing on the transition from oocyte to embryo. It aims to understand how these changes can influence cell fate and differentiation, which are crucial for successful reproduction. The study will explore the remodeling of the endoplasmic reticulum and mitochondria, as well as the behavior of RNA during this transition. By uncovering these mechanisms, the research seeks to fill important gaps in our understanding of developmental biology.
Who could benefit from this research
Good fit: Ideal candidates for this research are couples experiencing difficulty conceiving or individuals interested in understanding reproductive biology.
Not a fit: Patients who are not seeking to conceive or who are not affected by reproductive issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into reproductive health and potential treatments for infertility.
How similar studies have performed: While the specific focus on intracellular remodeling during early development is novel, related research has shown promising results in understanding cell differentiation and reproductive health.
Where this research is happening
CHAMPAIGN, UNITED STATES
- UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN — CHAMPAIGN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YANG, JING — UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- Study coordinator: YANG, JING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.