How CD4 T cells influence lung cell behavior
Official title: Lung epithelial cell reprogramming by CD4 T cells
Funded at University of Michigan at Ann Arbor · NIH-11059956 · Data updated 2026-11-12
This study is looking at how lung cells and a type of immune cell work together to help your body fight off bacterial infections like pneumonia, with the goal of finding new ways to boost lung health and immunity.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $248,999 |
| NIH project number | 5R00HL157555-05 |
| Project ID | NIH-11059956 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with lung conditions such as asthma or those who are prone to respiratory infections.
✕Less likely to help
Patients with non-respiratory conditions or those without any lung-related issues may not benefit from this research.
What this research studies
This research investigates the interaction between lung epithelial cells and CD4 T cells to enhance the body's ability to clear bacterial infections and maintain lung health. By understanding these cell communications, the study aims to develop new strategies for improving lung immunity and resilience, particularly during infections like pneumonia. The research employs advanced techniques in cell biology and immunology to explore how these interactions can be optimized for better health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for lung infections and conditions like asthma, enhancing overall lung health.
How similar studies have gone: Previous research has shown promising results in understanding cell interactions in lung immunity, suggesting that this approach could yield significant advancements.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Shenoy, Anukul T — University of Michigan at Ann Arbor
- Study coordinator: Shenoy, Anukul T
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.