How CD4 T cells influence lung cell behavior

Lung epithelial cell reprogramming by CD4 T cells

['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11059956

This study is looking at how lung cells and a type of immune cell work together to help your body fight off bacterial infections like pneumonia, with the goal of finding new ways to boost lung health and immunity.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-11059956 on ClinicalTrials.gov

What this research studies

This research investigates the interaction between lung epithelial cells and CD4 T cells to enhance the body's ability to clear bacterial infections and maintain lung health. By understanding these cell communications, the study aims to develop new strategies for improving lung immunity and resilience, particularly during infections like pneumonia. The research employs advanced techniques in cell biology and immunology to explore how these interactions can be optimized for better health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with lung conditions such as asthma or those who are prone to respiratory infections.

Not a fit: Patients with non-respiratory conditions or those without any lung-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for lung infections and conditions like asthma, enhancing overall lung health.

How similar studies have performed: Previous research has shown promising results in understanding cell interactions in lung immunity, suggesting that this approach could yield significant advancements.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.