How cannabis use in pregnancy may affect kids' body fat and heart/metabolic health

Prenatal exposure to cannabis and child cardiometabolic health outcomes

NIH-funded research University of Colorado Denver · NIH-11164789

This project looks at whether cannabis use during pregnancy is linked to changes in children's growth, body fat, and early heart and metabolic health.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11164789 on NIH RePORTER

What this research studies

You or your child could be part of data already collected in the Colorado Healthy Start pregnancy cohort, where pregnant people were enrolled between 2010 and 2014. The team will measure exposure to specific cannabinoids (like Δ9-THC and CBD), consider when during pregnancy exposure happened, and follow children's growth, body fat, glucose, and other cardiometabolic measures in early childhood. They will analyze whether certain cannabinoids or developmental windows raise risk and whether protective factors reduce that risk. Results will help parents and clinicians understand possible long-term effects of prenatal cannabis exposure.

Who could benefit from this research

Good fit: Ideal candidates are pregnant people or parents whose child experienced prenatal cannabis exposure, especially those enrolled in or similar to the Colorado Healthy Start cohort.

Not a fit: People without prenatal cannabis exposure or whose children are outside the ages covered by the cohort are unlikely to receive direct benefit from this work.

Why it matters

Potential benefit: If successful, findings could help pregnant people and clinicians better understand risks from prenatal cannabis and identify timing or protective factors to lower children's cardiometabolic risk.

How similar studies have performed: Previous studies consistently link prenatal cannabis to lower birth weight and small pilot work suggests faster early growth and higher adiposity, but the distinct roles of Δ9-THC versus CBD and sensitive exposure windows are not yet well tested.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.