How cannabis use affects young adults trying to quit cigarettes and vapes

The impact of cannabis and tobacco/nicotine product co-use in young adults: Prospective cessation evaluation and substitution

NIH-funded research Medical University of South Carolina · NIH-11178596

This project explores whether using cannabis makes it harder for young adults to stop smoking cigarettes or vaping nicotine.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11178596 on NIH RePORTER

What this research studies

If you're a young adult trying to quit cigarettes or nicotine vapes, researchers will follow people over time during a quit attempt to see how cannabis use relates to success. They'll collect information on which products people use, how often, cravings and withdrawal, and biological measures like breath or urine tests. The team will use behavioral-economics methods to understand choices and possible substitution between cannabis and nicotine. Participation may include surveys, brief visits or samples, and tracking over several months.

Who could benefit from this research

Good fit: Ideal candidates are young adults who currently use nicotine/tobacco (cigarettes or vapes) and also use cannabis, especially if they are planning to quit or cut back on nicotine.

Not a fit: People who do not use nicotine or cannabis, or those well outside the young adult age range, are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, the work could help clinicians tailor quitting support for young adults who also use cannabis and identify who needs extra help.

How similar studies have performed: Previous research is limited and mixed, with only a few secondary analyses from youth tobacco trials and no prior prospective quitting studies, so this approach is relatively untested.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.