How cannabis use affects quitting cigarettes

Determining the impact of cannabis use and severity on tobacco cessation outcomes: A prospective tobacco treatment trial

['FUNDING_R37'] · MEDICAL UNIVERSITY OF SOUTH CAROLINA · NIH-11196076

This project looks at whether adults who use both cannabis and cigarettes have different success when they try to quit smoking.

Quick facts

Phase['FUNDING_R37']
Study typeNih_funding
SexAll
SponsorMEDICAL UNIVERSITY OF SOUTH CAROLINA (nih funded)
Locations1 site (CHARLESTON, UNITED STATES)
Trial IDNIH-11196076 on ClinicalTrials.gov

What this research studies

You would join a tobacco-quit program where adults who smoke cigarettes are followed through a planned quit attempt, with extra enrollment of people who also use cannabis. Researchers track cigarette use, cannabis use, and e-cigarette use over time using surveys and biochemical measures. The study compares quit outcomes for cigarette-only smokers versus those who co-use cannabis or vaped nicotine products. The goal is to see how cannabis use changes during quitting and whether it makes stopping tobacco harder.

Who could benefit from this research

Good fit: Adults aged 21 and older who currently smoke cigarettes and are willing to try to quit, including those who also use cannabis or e-cigarettes.

Not a fit: People who do not smoke cigarettes, are under 21, or are not planning to attempt tobacco cessation would not be eligible and are unlikely to benefit.

Why it matters

Potential benefit: If successful, this work could help clinicians tailor quitting programs for people who also use cannabis.

How similar studies have performed: Earlier studies have shown mixed results but suggest cannabis co-use may hinder quitting, and this prospective trial builds on that prior work by oversampling co-users.

Where this research is happening

CHARLESTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.