How cannabis use affects brain development and behavior in adolescents
Cognitive flexibility and reward motivation in adolescent cannabis use: An investigation of neurobehavioral mechanisms and intrinsic resting state connectivity.
This study is looking at how using cannabis during the teenage years affects thinking, motivation, and brain connections, and it's for teens aged 14 to 17 who either use cannabis or don’t, to help us understand the potential risks of cannabis on their developing brains.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emma Pendleton Bradley Hospital NIH-funded |
| Lab location | 1 site (Riverside, UNITED STATES) |
| Project ID | NIH-10802444 on NIH RePORTER |
What this research studies
This research investigates the impact of cannabis use during adolescence on cognitive flexibility, reward motivation, and brain connectivity. By comparing adolescents who use cannabis with those who do not, the study aims to understand how cannabis disrupts normal brain development and influences behavior. The research will involve collecting data on symptoms, brain circuits, and behaviors from participants aged 14 to 17. The goal is to identify the neurobehavioral mechanisms that contribute to the risks associated with adolescent cannabis use.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 14 to 17 who are engaged in cannabis use or are typically developing without cannabis use.
Not a fit: Patients who are not adolescents or those who do not use cannabis may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for adolescents at risk of substance use disorders.
How similar studies have performed: Previous research has shown that understanding the neurobehavioral mechanisms of substance use in adolescents can lead to significant advancements in treatment and prevention, suggesting this approach has potential for success.
Where this research is happening
Riverside, UNITED STATES
- Emma Pendleton Bradley Hospital — Riverside, United States (Active)
Researchers
- Principal investigator: Thomas, Sarah Ann — Emma Pendleton Bradley Hospital
- Study coordinator: Thomas, Sarah Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.