How cannabis legalization affects mental health and substance use in people with psychosis

Impact of cannabis legalization and commercialization on substance use and mental health outcomes in psychosis

NIH-funded research Cambridge Health Alliance · NIH-11032923

This study looks at how the legalization and sale of cannabis affects people with psychotic disorders, especially in terms of their substance use and mental health, to help understand any risks they might face.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCambridge Health Alliance NIH-funded
Lab location1 site (Cambridge, United States)
Project IDNIH-11032923 on NIH RePORTER

What this research studies

This research investigates the impact of cannabis legalization and commercialization on individuals with psychotic disorders, particularly focusing on how these changes affect their substance use and mental health outcomes. The study will analyze existing data from national surveys and specialized clinics to understand the relationship between cannabis market expansion and the health of those with serious mental illnesses. By employing advanced statistical methods, the research aims to identify potential risks associated with cannabis use in this vulnerable population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who have been diagnosed with psychotic disorders, such as schizophrenia.

Not a fit: Patients who do not have a history of psychosis or are under the age of 21 may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of cannabis-related risks for individuals with psychosis.

How similar studies have performed: Previous research has indicated that cannabis use can exacerbate symptoms in individuals with psychosis, suggesting that this study's focus on commercialization effects is both relevant and necessary.

Where this research is happening

Cambridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.