How cannabis and nicotine use affects brain development in young adults

Cannabis and Nicotine Co-Use Influences on Protracted Development of Neural Structure and Function

NIH-funded research University of California, San Diego · NIH-11078840

This study is looking at how using cannabis and nicotine together affects the brain development of young adults aged 18-19, and it aims to help us understand the potential risks of using these substances during this important time in life.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11078840 on NIH RePORTER

What this research studies

This research investigates the combined effects of cannabis and nicotine use on brain development in young adults aged 18-19. By recruiting participants who use these substances in various patterns, the study aims to understand how their co-use influences brain structure, function, and cognitive abilities over time. Participants will undergo multiple assessments, including neuroimaging and behavioral interviews, to track changes in brain integrity and emotional health. The findings could provide insights into the risks associated with substance use during critical developmental periods.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults aged 18-19 who use cannabis and/or nicotine products.

Not a fit: Patients who do not use cannabis or nicotine products may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help identify the risks of cannabis and nicotine co-use, leading to better prevention and treatment strategies for substance use disorders.

How similar studies have performed: Previous research has indicated potential interactions between cannabis and nicotine, but this study aims to provide novel insights into their combined effects on brain development.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.